Thursday Night Football odds, spread, and line: Chargers vs. Chiefs predictions, NFL picks from a 17-5 expert

 Thursday Night Football odds, spread, and line: Chargers vs. Chiefs predictions, NFL picks from a 17-5 expert 

Thursday Night Football odds, spread, and line: Chargers vs. Chiefs predictions, NFL picks from a 17-5 expert

Why the Chargers are capable of covering

With Justin Herbert at the helm, the Chargers have enjoyed visits to Arrowhead Stadium. Los Angeles is 2-0 in Kansas City during Herbert's tenure, with the talented quarterback averaging 583 yards and seven touchdowns. Herbert is a top-tier option in any situation, as evidenced by his 279 yards and three touchdowns in Week 1. Herbert has thrown for more than 5,000 yards and 38 touchdowns dating back to the 2021 season and ranks in the top four in NFL history in passing yards and passing touchdowns through the first 33 games of a career.

As a result, the Chargers are extremely explosive, ranking in the top five in the league in passing offense, total offense, and scoring offense a year ago. Austin Ekeler, a running back, is not a bruiser, but he had more than 1,500 yards from scrimmage in 2021, ranking sixth in the NFL. Last season, Ekeler tied Jonathan Taylor for the league lead with 20 touchdowns, and the Chargers can take comfort in a defense that produced six sacks in the season opener four days ago.

Why the Chiefs are capable of covering

Kansas City isn't known for its defense, but the 2022 season opener established a solid foundation. In Week 1, the Chiefs limited the high-powered Cardinals offense to 282 total yards, while Arizona averaged only 4.4 net yards per pass attempt. Kansas City led the NFL in scoring in Week 1 with 44 points, and the Chiefs accumulated 488 total yards and 33 first downs. The Chiefs also had 33 first downs and went 6-for-6 in the red zone while converting more than 60% of third down chances.

Kansas City provided exceptional protection for Patrick Mahomes, allowing no sacks in the opener, and the Chiefs also ran the ball effectively against the Cardinals. With a rotation of running backs, the Chiefs used 27 carries to accumulate 128 rushing yards and a touchdown, and Kansas City finished the 2021 season ranked in the top four of the NFL in scoring offense and total offense.

Picking the Chiefs vs. the Chargers

White is leaning Under on Thursday Night Football, but he also believes a critical X-factor makes one side of the spread a must-back. He's only telling SportsLine what it is and which side of the Chargers vs. Chiefs spread to back.

Now, White has zeroed in on Chargers vs. Chiefs from every angle and issued a confident against-the-spread prediction. To see his TNF picks, go to SportsLine right now. Here are some NFL odds and betting lines for the Chiefs vs. Chargers matchup:

Chargers vs. Chiefs betting line: Chiefs -4

Over/under for Chargers vs. Chiefs: 54 points

Money line for Chargers vs. Chiefs: Chargers +175, Chiefs -210

LAC: The Chargers are 9-9 ATS in their last 18 games.

KC: In the last 21 games, the Chiefs are 11-10 against the spread.

Picks for the Chargers vs. Chiefs: SportsLine has predictions.

Following a thrilling first week of the 2022 NFL schedule, Week 2 kicks off on Thursday Night Football. The Kansas City Chiefs will host the Los Angeles Chargers in an AFC West matchup at Arrowhead Stadium. Both teams have star quarterbacks, with Patrick Mahomes leading the Chiefs and Justin Herbert emerging as the Chargers' face. The two teams split a pair of games in 2021, both winning on the road, and both won season-opening games last week to start the season 1-0.

The game begins at 8:15 p.m. ET in Kansas City. In the latest Chargers vs. Chiefs odds, Kansas City is a four-point home favorite, while the over/under, or total number of points Vegas believes will be scored, is 54. See what SportsLine expert R.J. White has to say before making any Chiefs vs. Chargers picks or NFL predictions for Thursday Night Football.

White, a CBS Sports Fantasy and gambling editor, consistently dominates as SportsLine's No. 1 NFL expert in picks against the spread, going 445-378-24 on his ATS picks from 2017-21, returning $2,542 to $100 players. He's also a whopping 17-5-1 in NFL picks involving the Chargers, so he's well-qualified for this pick.

He's well-known for winning the Westgate Las Vegas SuperContest twice in a row since 2015. White also cashed big on his NFL futures in 2021, including a 10-1 bet on Jonathan Taylor to be the NFL rushing leader. Anyone who has followed him is on the rise.

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